CBP said the number of encounters in January was the lowest since February 2021, the month after President Biden's inauguration.
In his State of the Union address, President Biden touted a policy that he says preceded a 97 percent drop in illegal immigration from four countries.
Customs and Border Protection reported a 53 percent increase in seizures of fentanyl along the southern border in November.
Originally instituted by Trump, the Title 42 public health order has been at the center of litigation since Biden took office.
A federal appellate court in D.C. previously denied an effort to stop an order bringing an end to Title 42 enforcement.
Democratic County Judge Ricardo Samaniego indicated illegal crossings in El Paso could spike to 5,000 daily when the use of Title 42 ends.
The U.S. Supreme Court previously decided that Biden could terminate the program, but the case is still awaiting its final resolution.
The agency reported more than 2.4 million encounters with illegal aliens along the southern border last fiscal year, an all-time record.
Commissioner Chris Magnus indicated that illegal immigration from Venezuela, Nicaragua, and Cuba accounts for many of the arrests in August.
Apprehensions, most of which occur in Texas sectors, have already surpassed the total from the last fiscal year.
Democratic Congressman Henry Cuellar has been a critic of the Biden administration on illegal immigration.
Enforcement encounters with illegal aliens subsided, with many of the expulsions still carried out under the Title 42 public health order.
